GHK-Cu (Copper Tripeptide-1) is a naturally occurring copper-binding tripeptide found in human plasma, saliva, and urine. It has been extensively studied for its effects on skin rejuvenation, wound healing, and anti-aging properties.

What is GHK-Cu?

GHK-Cu consists of the amino acid sequence glycine-histidine-lysine (GHK) bound to a copper ion (Cu2+). It is naturally produced in the human body and declines significantly with age.

  • Type: Naturally occurring tripeptide-copper complex
  • Molecular weight: ~340 Da (peptide component)
  • Applications: Skin care (cosmetic), wound healing research, anti-aging research

Mechanisms of Action

  • Collagen synthesis stimulation: Promotes fibroblast production of collagen, elastin, and glycosaminoglycans
  • Antioxidant activity: Copper binding provides superoxide dismutase-like activity
  • Anti-inflammatory effects: Reduces production of inflammatory cytokines
  • Wound healing acceleration: Promotes angiogenesis and tissue remodeling
  • Gene expression modulation: Research shows effects on 4,000+ genes involved in repair and regeneration

Safety Profile

GHK-Cu has one of the most favorable safety profiles of any research peptide. It is naturally occurring in the human body, with long history of safe topical use in cosmetic products.

Disclaimer

This information is for educational and research purposes only. Injectable GHK-Cu is not approved for human therapeutic use. Always consult qualified healthcare professionals for medical guidance.